Hospitals concerned with potential exposure to Creutzfeldt-Jacob Disease (CJD) often take extreme measures from treating instruments with heavy doses of bleach to incinerating anything that might have come in contact with the patient. The reaction is warranted given the risks. However, we, at Case Medical, have developed a better approach to the problem which may not be a cure, but can be more than an ounce of prevention. CJD, which is the most common prion related disease in humans, can be caused by exposure to contaminated devices. Once infected, it can take years, often decades, before patients start to show symptoms. Common symptoms include imbalance and incoordination, memory loss, impaired thinking and psychiatric symptoms such as depression and anxiety. Upon onset of symptoms, CJD can progress very quickly and prove to be fatal within a year. Infected patients can transmit the disease while asymptomatic, making detection nearly impossible. CJD can only be confirmed postmortem or with a brain biopsy, which rarely occurs. While prion diseases can occur for different reasons including consumption of infected meat, inherited predisposition, the more relevant risk for humans is in a healthcare setting via contaminated instruments.